Tonight's pitchers: Guthrie vs. Buchholz

RHP Jeremy Guthrie (10-14, 5.06) tonight is set to make his 30th start of this year, his 16th at home and the 11th of his career vs. Boston. Guthrie was 3-1, 1.33 over his previous four starts before taking the loss Sunday vs. New York. Over 5 2/3 at Yankee Stadium, he allowed 12 hits and five runs. Still, over the past five starts, Guthrie is 3-2, 2.48. Guthrie is the AL leader in runs, losses and homers allowed this year with 30. Of those 30, 12 have come vs. the Yankees and Red Sox, who each have six off the right hander. Guthrie, 2009 season: First half: 6-8, 5.35 in 18 starts Second half: 4-6, 4.65 in 11 starts Guthrie has allowed 2ER or less eight times this year, including in four of his past five starts. The Orioles are 11-18 in his starts this season. In 15 homes starts, Guthrie is 5-7, 4.74. Guthrie vs. Boston: 2009: 0-2, 8.00, 3 starts (18IP, 25H, 6 HR) Career: 1-4, 4.74, 10 starts (62 2/3IP, 74H, 29B, 40K) RHP Clay Buchholz (5-3, 3.66) tonight will make his 13th start of this season, his 7th on the road and the 6th of his career against a Baltimore team he once no-hit. Buchholz has been pitching very well recently. Over his last four starts, he is 3-0, 1.59. He is 4-0 over his last six starts. He has allowed 2ER or less in eight of his 12 starts on the year and the Red Sox are 8-4 when he starts, winning six in a row. Buchholz, 2009 season: Home: 2-1, 2.72, six starts Road: 3-2, 4.83, six starts On September 1, 2007, in just his second Major League start, Buchholz pitched a no-hitter against the Orioles with nine strikeouts. He began this season at Triple-A and, after going 7-2, 2.36 in 16 Pawtucket starts, was recalled by the Sox in mid July. The 25-year-old righty has had two very different starts vs. Baltimore this year. One where he allowed seven runs in four innings, and one where he pitched seven shutout innings. Buchholz vs. Baltimore: 2009: 1-0, 5.73, two starts (11IP, 12H, 7R-ER) Career: 3-2, 4.75, six games, five starts (30 1/3IP, 21H, 18B, 26K). O's hitters, career vs. Buchholz: Andino: 0-1 Fiorentino: 0-1 Izturis: 0-2 Markakis: 1-10, rbi Moeller: 2-2, rbi Mora: 1-6, rbi Pie: 1-5 Roberts: 6-14, 3 rbi Scott: 0-7 Turner: 0-1 Wieters: 2-3 Wigginton: 2-4, HR, 2 rbi