The Orioles begin their three-game series in Houston with Colton Cowser out of the lineup for the second consecutive day.
Ryan O’Hearn is making his second start in left field, with Cedric Mullins in center and Anthony Santander in right.
Jordan Westburg is the third baseman. Adley Rutschman is serving as designated hitter.
Texas native Grayson Rodriguez is making his first career start in Houston. He faced the Astros last season at Camden Yards and allowed two runs in six innings.
Rodriguez has made three starts this month and allowed five earned runs in 19 1/3 innings. He’s walked two batters and struck out 16.
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