For the Orioles, it was a tough start to a nine-game road trip.
Mike Aviles led off the last of the 11th with a homer to left off Brian Matusz as Cleveland beat the Orioles 2-1 with the walk-off win. Aviles hit a 77 mph breaking ball for his fourth homer.
The Orioles fall to 69-51 and their eight-game winning streak in series openers comes to an end.
The Orioles tied the game 1-1 in the top of the eighth with a two-out rally. With none on, Nelson Cruz singled to end Corey Kluber's night. Right-hander Bryan Shaw came on and gave up back-to-back singles to Delmon Young and J.J. Hardy that tied this game.
Hardy went 2-for-4 with an RBI as he returned to the lineup for the first time since Saturday. He missed three games with a sprained left thumb. Over his last seven games, he is 13-for-27 with two homers and eight RBIs.
Zach Walters' solo homer off Wei-Yin Chen in the last of the fifth gave Cleveland a 1-0 lead. He hit a 2-2 pitch just over the left-field wall for his second homer with Cleveland and fifth on the year. He had three earlier with Washington.
Chen has allowed 20 homers on the year, 17 to right-handed batters.
But that was the only run Chen allowed in a very strong outing. Over seven innings, he gave up just four hits with one walk and six strikeouts. Chen has pitched to an ERA of 2.51 in five starts since the All-Star break.
The Orioles could not score off Kluber until the eighth. The Indians ace went 7 2/3 innings, allowing five hits and one run with two walks and 10 strikeouts. In two starts against the Orioles in 2014, he has given up one run over 14 2/3 frames. In his last five starts, he's allowed two earned runs in 39 innings.
For the game, the Orioles went 1-for-6 with runners in scoring position and left 10 runners on base.
The Orioles fall to 35-25 on the road, 9-15 against the American League Central and 17-9 since the All-Star break.
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