Bryce Harper's stay in the second spot in the lineup lasted one day.
Nationals manager Matt Williams returned Harper to sixth in the order for the fourth time in five games since the outfielder was activated from the disabled list. Batting second Friday, Harper went 0-for-4.
Anthony Rendon moves back up to second after hitting sixth. Rendon is riding an eight-game hitting streak.
The Nats won't be facing Jeff Samardzija after the Cubs traded the right-hander (along with right-hander Jason Hammel) to the Athletics on Friday night.
Right-hander Carlos Villanueva will be starting in Samardzija's place, having gone 4-5 with a 5.91 ERA in 22 games (four starts) with Chicago this season. Villanueva hasn't started since April 25 with his ERA at 9.95. He has performed much better since, going 3-0 with a 3.04 ERA in 16 relief appearances.
The Nats answer with lefty Gio Gonzalez, who has pitched 13 scoreless innings over his last two starts.
For the Nationals
CF Denard Span
2B Anthony Rendon
RF Jayson Werth
1B Adam LaRoche
3B Ryan Zimmerman
LF Bryce Harper
SS Ian Desmond
C Wilson Ramos
LHP Gio Gonzalez
For the Cubs
CF Junior Lake
RF Justin Ruggiano
1B Anthony Rizzo
SS Starlin Castro
C Wellington Castillo
3B Mike Olt
LF Chris Coghlan
2B Darwin Barney
RHP Carlos Villanueva
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