The Padres scored first against Nationals right-hander Tanner Roark.
Right fielder Matt Kemp blasted a 3-1 pitch over the left-center field wall to give San Diego a 1-0 lead.
The Nationals quickly answered in the bottom on the first. With one out, Jayson Werth slammed a home run over the left field wall and the game was even up at 1-1.
Werth now has a 26-game on-base streak with the first-inning homer.
Later in the inning, Bryce Harper walked and then stole second base. It was his 15th stolen base of the season, three away from his career high of 18 in 2012.
Wilson Ramos then singled to right to give the Nats the lead 2-1.
After one and a half innings, Nats lead 2-1 over the Padres.
Update: Kemp launched a three-run shot in the top of the fifth, part of a four-run outburst by the Friars. Kemp got a hold of a 2-1 Roark offering and placed in the seats below the Budweiser Brew House. The Padres lead 5-2 in the middle of the fifth. It marks Kemp's ninth career multi-homer game.
Update II: Roark lasts five innings, allowing five runs on four hits, two of them homers, with two walks and four strikeouts. He threw 93 pitches, 54 for strikes.
Update III: Daniel Murphy launched his 19th homer of the season, a solo shot on a 2-2 offering from Padres veteran lefty Brad Hand. The Padres lead now 5-3 after eight innings.
Update IV: The Nationals allowed two big homers from Kemp, similar to what Justin Turner was able to do against Stephen Strasburg.
Jonathan Papelbon pitched a solid scoreless ninth inning, striking out one.
The Padres won their third straight over the Nationals and snapped a four-game skid with a 5-3 victory. The Nationals have now lost four of their last five games.
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